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a-PHP, (α-Pyrrolidinohexanophenone), or PV-7 is a compound of the substituted cathinone and substituted pyrrolidine chemical classes. Its structure is comprised of hexanal bound to a phenyl ring at the1 position and the nitrogen of a pyrrolidine ring at the 2 position.
Alpha-PHP (a-PHP) is thus a synthetic stimulant drug of the cathinone class and was already developed and patented in the 1960s. It has no therapeutic or medical use. Alpha-PHP is an uptake inhibitor at the DAT, SERT and NET, based on its ability to inhibit uptake and inability to induce release. In general, the intensity of the effects of this substance is comparable to strong stimulants such as Methamphetamine, MDPV and alpha-PVP.
a-PHP has formal name: 1-Phenyl-2-(pyrrolidin-1-yl)hexan-1-one. The chemical formula for a-PHP is C12H20NO with a molecular weight of 192.32
Since this substance (a-PHP) is extremely potent, consumers suggest to take a maximum of 5-10mg oral, nasal, sublingual and rectal maximal 4-7mg and a maximum of 2- 4mg for inhalation or intravenous application.
Below is a list of effects from a-PHP:
- Stimulation (stimulating, awakening) - alpha-PHP is one of the very strong stimulating pyrovalerones
- Strongly appetite –reducing effect (stronger than many other stimulants)
- Increased concentration and performance – However, due to the highly confusing, euphoric, stimulating or anxiety-enhancing and other side effects, alpha-PHP is not suitable as a cognitive enhancer or performance enhancer, even if a certain increase in concentration and performance is felt
- Aphrodisiac - increase sexual desire and delay orgasm
- Euphoric - The euphoria occurs above all after the onset of action, then decreases slowly after a short time and leaves the consumer with the feeling of wanting more; i.e., craving
- Improvement of the music sense In general, the intensity of the effects of this substance is comparable to strong stimulants such as methamphetamine (Crystal Meth), MDPV and α-PVP
The toxicity and long-term health effects of recreational a-PHP use do not seem to have been studied in any scientific context and the exact toxic dosage is unknown.
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a-PHP is intended for research and forensic purposes in a controlled laboratory for study only and is NOT intended for human consumption.
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