2'-Oxo-PCE (also known as as Eticyclidone, and O-PCE) is a novel synthetic dissociative substance of the arylcyclohexylamine chemical class that produces dissociative, anesthetic, stimulating and hallucinogenic effects when administered. It is structurally related to deschloroketamine (also known as 2'-Oxo-PCM, O-PCM, or DCK) as well as MXE and is speculated to produce its effects through its affinity as an NMDA receptor antagonist.

2'-Oxo-PCE (Eticyclidone, O-PCE) is an example of a contemporary designer drug specifically chosen to mimic and/or replace the functional and structural features of its predecessors. 2'-Oxo-PCE (Eticyclidone, O-PCE) is being marketed and sold as a designer drug replacement for MXE and other dissociatives for recreational purposes.

In comparison to DCK, Ketamine and MXE, 2-Oxo-PCE can be described as generally more stimulating with fewer cognitive and sensory suppressions. The first half of its duration presents primarily stimulating effects with minimal dissociation whilst the second half is primarily dissociating with minimal stimulation.

2'-Oxo-PCE (Eticyclidone, O-PCE) is intended for research and forensic purposes in a controlled laboratory for study only and is NOT intended for human consumption.